Pancreas Transplantation

Surgical Equipment 

Anesthesia Equipment 

Surgical Drapes and Sterile Supplies 

Surgical Microscopes 

Perfusion Pump 

Monitoring Equipment 

Informed Consent:  

Educate patients and their family on procedure, risks, benefits, and post-transplant regimen importance. 

The patient is positioned in a supine position and general anesthesia is administered. 

Anatomy of Pancreas 

Step 1: Incision and Exposure 

Surgeons give a midline abdominal incision from xiphoid process to pubic symphysis accesses abdominal cavity. 

Abdominal cavities are examined to locate blood vessels before organ implantation. 

Step 2: Donor Pancreas Preparation 

Donor pancreas is carefully prepared with duodenum and spleen, then preserved in cold solution to minimize injury. 

Step 3: Vascular Anastomosis: 

Prepare iliac vessels or superior mesenteric artery and portal vein for anastomosis.  

Connect donor’s superior mesenteric artery and splenic artery to recipient’s iliac artery with end-to-side anastomosis. 

Step 4: Exocrine Drainage: 

Donor duodenum connected to recipient’s small intestine in end-to-side anastomosis, it is common method which allows pancreatic enzymes to drain in intestine. 

Step 5: Reperfusion and Closure 

Clamps are removed to restore blood flow in pancreas, monitor for bleeding and ensure perfusion. 

Abdominal incision closed in layers with sutures. 

 Pancreas transplantation

Surgical Complications as follows: 

Pancreatic Fistula 

Bleeding 

Thrombosis 

Stenosis 

Vascular Complications as follows:  

Hemorrhage 

Late Complications as follows: 

Cardiovascular Disease 

Renal Dysfunction 

Malignancies 

Chronic Rejection